Article

The Multiple Sclerosis Walking Scale-12 (MSWS-12) is a multi-item rating scale
used to assess the perspectives of patients about the impact of MS on their
walking ability. The aim of this study was to examine the reliability and
validity of the MSWS-12 in Persian speaking patients with MS. The MSWS-12
questionnaire was translated into Persian language according to internationally
adopted standards involving forward-backward translation, reviewed by an expert
committee and tested on the pre-final version. In this cross-sectional study, 100
participants (50 patients with MS and 50 healthy subjects) were included. The
MSWS-12 was administered twice 7 days apart to 30 patients with MS for test and
retest reliability. Internal consistency reliability was Cronbach's alpha 0.96
for test and 0.97 for retest. There were no significant floor or ceiling effects.
Test-retest reliability was excellent (intraclass correlation coefficient [ICC]
agreement of 0.98, 95% CI, 0.95-0.99) confirming the reproducibility of the
Persian MSWS-12. Construct validity using known group methods was demonstrated
through a significant difference in the Persian MSWS-12 total score between the
patients with MS and healthy subjects. Factor analysis extracted 2 latent factors
(79.24% of the total variance). A second factor analysis suggested the 9-item
Persian MSWS as a unidimensional scale for patients with MS. The Persian MSWS-12
was found to be valid and reliable for assessing walking ability in Persian
speaking patients with MS.
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