Article

OBJECTIVE: To determine the efficacy of 2 different interventions (cognitive
behavioral therapy [CBT] and supportive psychotherapy [SPT]) to treat
post-traumatic brain injury (TBI) depression. PARTICIPANTS:
A sample of 77
community-dwelling individuals with a TBI, and a diagnosis of depression.
Participants were randomized into treatment conditions either CBT or SPT and
received up to 16 sessions of individual psychotherapy. MEASURES: Participants
completed the Structured Clinical Interview for DSM-IV and self-report measures
of depression (Beck Depression Inventory-Second Edition), anxiety (State-Trait
Anxiety Inventory), perceived social support (Interpersonal Support Evaluation
List), stressful life events (Life Experiences Survey), and quality of life (QOL)
before beginning and immediately following treatment. RESULTS: No significant
differences were found at baseline between CBT and SPT groups on demographic
factors (sex, age, education, race, and time since injury) or baseline measures
of depression, anxiety, participation, perceived social support, stressful life
events, or QOL. Analyses of variance revealed significant time effects for the
Beck Depression Inventory-Second Edition, State-Trait Anxiety Inventory, and QOL
outcome measures but no group effects. Intention-to-treat mixed effects analyses
did not find any significant difference in patterns of scores of the outcome
measures between the CBT and SPT intervention groups. CONCLUSIONS: Both forms of
psychotherapy were efficacious in improving diagnoses of depression and anxiety
and reducing depressive symptoms. These findings suggest that in this sample of
individuals with TBI, CBT was not more effective in treating depression than SPT,
though further research is needed with larger sample sizes to identify different
components of these interventions that may be effective with different TBI
populations. ClinicalTrials.gov Identifier: NCT00211835.

Langue : ANGLAIS