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Where do injectable stem cell treatments apply in treatment of muscle, tendon, and ligament injuries ?

MAUTNER K; BLAZUK J
PM & R , 2015, vol. 7, n° Suppl. 4, p. S33-S40
Doc n°: 174459
Localisation : Documentation IRR

D.O.I. : http://dx.doi.org/DOI:10.1016/j.pmrj.2014.12.012
Descripteurs : DA6 - TRAITEMENTS - APPAREIL LOCOMOTEUR

Treatment options for muscle, tendon, and ligament injuries span a constantly
evolving spectrum. For years, treatments focused on symptomatic relief. Closer
scrutiny of symptomatic treatment suggests that the provision of transient relief
of symptoms may have caused more harm than good. Cortisone injections provide a
trade-off of short-term relief for poorer long-term outcomes. When conventional
treatment failed, patients have faced limited options including surgery, which
has increased risk and limited efficacy. Regenerative injections offer a more
robust option for soft tissue disease. Basic science and clinical studies show
conflicting results to support the use of platelet-rich plasma injections for
soft tissue disorders, and even fewer trials have focused on injectable stem
cells with limited findings. Additional studies are needed to determine the
potential benefits of this regenerative therapy.
CI - Copyright (c) 2015 American Academy of Physical Medicine and Rehabilitation.
Published by Elsevier Inc. All rights reserved.

Langue : ANGLAIS

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