Article

Recent studies indicate that physically demanding work is a risk
factor for heart disease among men, especially those with low or moderate
physical activity during leisure time. Among women, present evidence is
inconclusive. DESIGN: The design was a prospective cohort study. METHODS: This
investigation in the Danish Nurse Cohort Study included 12,093 female nurses aged
45-64 years, who answered a self-report questionnaire on physical activity at
work and during leisure time, known risk factors for ischaemic heart disease
(IHD) and occupational factors at baseline in 1993. Information on the 15-year
incidence of IHD was obtained by individual linkage in the National Register of
Hospital Discharges to 2008. RESULTS: During follow-up 580 participants were
hospitalised with IHD. A significant interaction between occupational and leisure
time physical activity was found with the lowest risk of IHD among nurses with
the combination of moderate physical activity at work and vigorous physical
activity during leisure time. Compared to this group high physical activity at
work was associated with a higher risk of IHD at all levels of physical activity
during leisure time increasing from hazard ratio 1.75 (95% confidence interval
(CI) 1.10-2.80) among nurses with vigorous physical activity during leisure time
to 2.65 (95% CI 1.44-4.88) among nurses being sedentary during leisure time.
CONCLUSIONS: This study among Danish nurses suggests that high physical activity
at work is a risk factor for IHD among women. Vigorous physical activity during
leisure time lowered but did not completely counteract the adverse effect of
occupational physical activity on risk of IHD.
CI - (c) The European Society of Cardiology 2014.

Langue : ANGLAIS