Article

OBJECTIVES: To assess the prevalence of fatigue, pain, anxiety, and depression in
adults with Duchenne muscular dystrophy (DMD), and to analyze their relationship
with health-related quality of life. DESIGN: Cross-sectional study. SETTING: Home
of participants. PARTICIPANTS: Adults (N=80) with DMD. INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: Fatigue was assessed with the Fatigue Severity
Scale; pain with 1 item of the Medical Outcomes Study 36-Item Short-Form Health
Survey and by interview; and anxiety and depression by using the Hospital Anxiety
and Depression Scale. Health-related quality of life was assessed using the World
Health Organization Quality of Life Scale-Brief Version. Associations between
these conditions and quality of life were assessed by means of univariate and
multivariate logistic regression analyses. RESULTS: Symptoms of fatigue (40.5%),
pain (73.4%), anxiety (24%), and depression (19%) were frequently found.
Individuals often had multiple conditions. Fatigue was related to overall quality
of life and to the quality-of-life domains of physical health and environment;
anxiety was related to the psychological domain. CONCLUSIONS: Fatigue, pain,
anxiety, and depression, potentially treatable symptoms, occur frequently in
adults with DMD and significantly influence health-related quality of life.
CI - Copyright (c) 2015 American Congress of Rehabilitation Medicine. Published by
Elsevier Inc. All rights reserved.

Langue : ANGLAIS