Article

OBJECTIVES: The aim was to study changes over time for multiple outcomes based on
the International Classification of Functioning, Disability, and Health in
patients with aneurysmal subarachnoid hemorrhage and to compare long-term
outcomes with norms. DESIGN: A prospective cohort study with 4-yr follow-up was
conducted. Main outcome measures were as follows: Center for Epidemiologic
Studies-Depression Scale, Fatigue Severity Scale, Trail Making Test A and B,
Barthel Index, Sickness Impact Profile-68, Impact on Participation and Autonomy
Questionnaire, Social Support List-12, Multidimensional Health Locus of Control
Scales, COOP-WONCA Charts, and Short Form-36 Health Survey. RESULTS: Seventy-six
patients with aneurysmal subarachnoid hemorrhage were included. Measurements were
done at T1 = 0.4 yrs (SD, 0.3 yrs) and T2 = 3.9 yrs (SD, 0.7 yrs) after onset.
Significant improvements over time were found for Barthel Index (T1 = 18.5; T2 =
19.5; P = 0.023), Trail Making Test B (T1 = 119.4; T2 = 104.6; P = 0.025), Social
Support List-12 total score (T1 = 31.1; T2 = 32.7; P = 0.042) and esteem support
(T1 = 10.2; T2 = 10.9; P = 0.027), Multidimensional Health Locus of Control
Scales (physician-orientation) (T1 = 21.8; T2 = 19.2; P = 0.020), and Short
Form-36 Health Survey (role-emotional) (T1 = 54.6; T2 = 73.9; P = 0.048). Center
for Epidemiologic Studies-Depression Scale, Fatigue Severity Scale, Sickness
Impact Profile-68, and Short Form-36 Health Survey scores remained stable over
time. A decline was found for COOP-WONCA (overall-health) (T1 = 2.3; T2 = 2.7; P
= 0.021). At 4-yr follow-up, proportions of depression (27%) and fatigue (60%)
were larger and scores on the Fatigue Severity Scale (mean [SE], 4.3 [0.2]),
Trail Making Test A (mean [SE], 51.3 [3.9]), and Trail Making Test B (mean [SE],
104.4 [0.2]) were significantly worse than norm scores. CONCLUSIONS: Many
patients with aneurysmal subarachnoid hemorrhage had fairly good long-term
outcomes, but problems in executive functioning, mood, and fatigue still exist at
long-term follow-up.

Langue : ANGLAIS