Article

OBJECTIVE: To evaluate the current evidence of the effectiveness of botulinum
toxin (BTX) treatment for shoulder pain. DATA SOURCES: Ovid MEDLINE In-Process
and Other Non-Indexed Citations, Ovid MEDLINE, Ovid EMBASE, Web of Science, and
Scopus were searched from inception through week 18 of 2015. STUDY SELECTION:
Randomized controlled trials comparing the clinical efficacy (pain intensity and
shoulder range of motion [ROM]) of BTX injection to conventional therapy (steroid
or placebo injection) were included. DATA EXTRACTION: Two reviewers independently
screened abstracts and full texts. The results of the pain intensity and shoulder
ROM were extracted and presented in the form of mean and SD. We constructed
random-effects models and calculated the mean difference (MD) for continuous
outcomes. A total of 219 articles were identified, of which 9 articles were
eligible for the final analysis. DATA SYNTHESIS: The analysis indicated a
statistically significant decreased pain score in the BTX therapy group compared
with the control group, with the MD=1.35 (95% confidence interval [CI], .80-1.91;
P<.001; I(2)=81%). Patients who received BTX therapy were more likely to have a
significant increase in shoulder abduction ROM than patients in the control
group, with the MD=8.02 (95% CI, 1.17-14.88, P=.02, I(2)=89%). CONCLUSIONS:
Compared with conventional (steroid or placebo injection) therapy, BTX injections
have beneficial effects for adult patients with shoulder pain, evidenced by
improved pain scores and ROM.
CI - Copyright (c) 2015 American Congress of Rehabilitation Medicine. Published by
Elsevier Inc. All rights reserved.

Langue : ANGLAIS