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The Molecular Pathophysiology of Concussive Brain Injury

BARKHOUDARIAN G; HOVDA DA; GIZA CC
PHYS MED REHABIL CLIN N AM , 2016, vol. 27, n° 2, p. 373-393
Doc n°: 178516
Localisation : Documentation IRR

D.O.I. : http://dx.doi.org/DOI:10.1016/j.pmr.2016.01.003
Descripteurs : AF3 - TRAUMATISME CRANIEN

Concussion, or mild traumatic brain injury (TBI), affects millions of patients
worldwide. Understanding the pathophysiology of TBI can help manage its
repercussions. The brain is significantly altered immediately following mild TBI
because of metabolic, hemodynamic, structural, and electrophysiologic changes.
This process affects cognition and behavior and can leave the brain vulnerable
for worse injury in the setting of repeat insult.
This article is an update of
our previously published review, reporting relevant and current studies from the
bench to the bedside of mild TBI. Understanding the pathobiology can help prevent
and treat mild TBI.
CI - Copyright (c) 2016 Elsevier Inc. All rights reserved.

Langue : ANGLAIS

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