Article

OBJECTIVE: To estimate the relative contribution of psychological factors next to
sociodemographic and premorbid/stroke-related factors to the risk of developing
symptoms of depression and anxiety after stroke.
DESIGN: Multicenter,
longitudinal cohort study. SETTING: Patients after stroke from 6 general
hospitals. PARTICIPANTS: Patients (N=331) were included at stroke onset and
followed up 2 and 12 months after stroke. INTERVENTIONS: Not applicable. MAIN
OUTCOME MEASURES: Sociodemographic and premorbid/stroke-related information was
recorded during hospital admission, whereas psychological characteristics were
determined with postal questionnaires 2 months poststroke. Symptoms of depression
and anxiety were assessed with the Hospital Anxiety and Depression Scale (HADS) 2
and 12 months poststroke. Multivariable logistic analysis was performed to
analyze the influence of sociodemographic, premorbid/stroke-related, and
psychological characteristics on depressive symptoms (depression subscale of HADS
>7) and symptoms of anxiety (anxiety subscale of HADS >7) 1 year after stroke.
RESULTS: Early depression, stroke severity, posterior cerebral artery stroke, and
neuroticism independently explained the variance of depressive symptoms 1 year
poststroke (discriminative power, 83%; adjusted R(2) value, 36%). Neuroticism and
early anxiety independently explained the variance of symptoms of anxiety 1 year
poststroke (discriminative power, 88%; adjusted R(2) value, 44%). Based on these
predictive models, nomograms were constructed to visually reflect the individual
contribution of each risk factor to the development of long-term mood disorders
after stroke. CONCLUSIONS: Psychological characteristics are important risk
factors for poststroke symptoms of depression and anxiety.
CI - Copyright (c) 2016 American Congress of Rehabilitation Medicine. Published by
Elsevier Inc. All rights reserved.

Langue : ANGLAIS