Article

OBJECTIVES: To compare the measurement properties and responsiveness to change of
the Patient Health Questionnaire-9 (PHQ-9), the Hopkins Symptom Checklist-20
(HSCL-20), and the Hamilton Depression Rating Scale (HAM-D) in people with spinal
cord injury (SCI) diagnosed with major depressive disorder (MDD). DESIGN: Secondary analysis of depression symptoms measured at 6 occasions over 12 weeks
as part of a randomized controlled trial of venlafaxine XR for MDD in persons
with SCI. SETTING: Outpatient and community settings. PARTICIPANTS: Individuals
(N=133) consented and completed the drug trial. Eligibility criteria were age at
least 18 years, traumatic SCI, and diagnosis of MDD. INTERVENTIONS: Venlafaxine
XR. MAIN OUTCOME MEASURES: Patients completed the PHQ-9 and the HSCL-20
depression scales; clinical investigators completed the HAM-D and the Structured
Clinical Interview for Diagnostic and Statistical Manual of Mental
Disorders-Fourth Edition (DSM-IV) Dissociative Disorders, which was used as a
diagnostic criterion measure. RESULTS: All 3 instruments were improved with
rating scale analysis. The HSCL-20 and the HAM-D contained items that misfit the
underlying construct and that correlated weakly with the total scores. Removing
these items improved the internal consistency, with floor effects increasing
slightly. The HAM-D correlated most strongly with Structured Clinical Interview
for DSM-IV Dissociative Disorders diagnoses. Improvement in depression was
similar on all outcome measures in both treatment and control groups.
CONCLUSIONS: The psychometric properties of the revised depression instruments
are more than adequate for routine use in adults with SCI and are responsive to
clinical improvement. The PHQ-9 is the simplest instrument with measurement
properties as good as or better than those of the other instruments and required
the fewest modifications.
CI - Copyright (c) 2016 American Congress of Rehabilitation Medicine. Published by
Elsevier Inc. All rights reserved.

Langue : ANGLAIS