Article

There are still limitations as to the understanding of the cognitive-postural
control relationship in people with multiple sclerosis (PwMS). The aim of the
current study' was to examine the relationship between cognition with measures of
posturography in PwMS.
The study was cross-sectional comprising 253 PwMS (162
women) with a mean age of 42.0 (SD=14.0). All participants completed a
computerized cognitive test battery designed to evaluate multiple cognitive
domains (Mindstreams; NeuroTrax) and static posturography tests (Zebris Medical
GmbH). PwMS were divided into four levels of disability on the basis of their
Expanded Disability Status Scale (EDSS) score: very mild (EDSS: 0-2.0), mild
(EDSS: 2.5-3.5), moderate (EDSS: 4.0-5.5), and severe (EDSS: 6.0-6.5; using a
walking aid). Significant correlations were observed between cognitive domains
and posturography measures. However, the correlations were different between the
disability subgroups. For the mild group, significant correlation scores were
observed between the balance measures to the executive function and motor skills
cognitive domains (Pearson's rho= approximately 0.3 and approximately 0.4,
respectively). As for the moderate group, significant correlation scores were
observed in memory and verbal function (Pearson's rho= approximately 0.4 and
approximately 0.4, respectively). Attention was the only cognitive domain
correlated significantly with posturography measures in the severe group
(Pearson's rho= approximately 0.55). Our study found that posturography measures
are related to cognition in PwMS. However, the associations vary in terms of
cognitive domains and disability levels.

Langue : ANGLAIS