Article

This study calculated knee contact forces (KCF) and its relations with
knee external knee adduction moments (KAM) and/or flexion moments (KFM) during
the stance phase of gait in patients with early osteoarthritis (OA), classified
based on early joint degeneration on Magnetic Resonance Imaging (MRI).
We aimed
at assessing if altered KCF are already present in early structural degeneration.
DESIGN: Three-dimensional motion and ground reaction force data in 59 subjects
with medial compartment knee OA (N=23 established OA, N=16 early OA, N=20
controls) were used as input for a musculoskeletal model. KAM and KFM, and KCF
were estimated using OpenSim software. RESULTS: No significant differences were
found between controls and subjects with early OA. In early OA patients, KAM
significantly explained 69% of the variance associated with the first peaks KCF
but only KFM contributed to the second peaks KCF. The multiple correlation,
combining KAM and KFM, showed to be higher. However, only 20% of the variance of
second peak KCF was explained by both moments in established OA. CONCLUSION: KCF
are not increased in patients with early OA, suggesting that knee joint overload
is more a consequence of further joint degeneration in more advanced stages of
OA. Additionally, our results clearly show that KAM is not sufficient to predict
joint loading at the end of the stance, where KFM contributes substantially to
the loading, especially in early OA.
CI - Copyright (c) 2016 Elsevier B.V. All rights reserved.

Langue : ANGLAIS