Article

Balance impairments are common in patients with hereditary spastic
paraplegia and are among the most debilitating symptoms, as they frequently
result in falls and fall-related injuries. Several features of hereditary spastic
paraplegia contribute to balance impairments and multiple treatment options
exist. However, an overview of these underlying mechanisms and their treatment is
currently lacking. This paper reviews the pathophysiology, diagnostic
workup, and management of balance impairments in hereditary spastic paraplegia.
Recommendations are based on scientific evidence, when available, and otherwise
reflect practice-based evidence supported by clinical experience. CONCLUSION:
Through diligent history-taking and clinical examination, followed by
multidisciplinary treatment tailored to the identified underlying mechanisms,
balance capacities can be improved in patients with hereditary spastic paraplegia
and at least a proportion of falls can be prevented.

Langue : ANGLAIS