Article

OBJECTIVES: To determine the prevalence of sarcopenia in stroke survivors using
different methodologies, and compare a subset of the stroke group to age-, sex-,
and body mass index (BMI)-matched nonstroke control counterparts. DESIGN: Cohort
study. SETTING: A Veterans Affairs medical center and a university hospital.
PARTICIPANTS: Mild to moderately disabled participants >6 months after onset of
stroke aged 40 to 84 years
(N=190, 61% men, 57% African American; mean BMI +/-
SEM, 29+/-1kg/m2). INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES:
Dual-energy x-ray absorptiometry scans to assess appendicular lean mass (ALM).
Rates of sarcopenia were determined using 4 established methods: (1) ALM/height2
(ALM/ht2); (2) European Working Group on Sarcopenia in Older Persons; (3)
International Working Group on Sarcopenia; and (4) ALM/BMI. RESULTS: Sarcopenia
prevalence in our stroke cohort ranged between 14% and 18%. The stroke survivor
subset (n=38) matched one-for-one with control counterparts for race, sex, age
+/-4 years and BMI +/-2.5kg/m2 had higher prevalence rates compared with their
nonstroke counterparts (13.2% vs 5.3%, P<.0001). ALM/ht2 was related to 6-minute
walking speed (r=.28, P<.01) and peak oxygen consumption (L/min: r=.58, P<.0001)
for the stroke group. CONCLUSIONS: Stroke survivors show an elevated prevalence
of sarcopenia when considering age, sex, and race compared with nonstroke
individuals.
CI - Published by Elsevier Inc.

Langue : ANGLAIS