Article

This study assessed predictive values of fidgety movement assessment (FMA)
in a large sample of infants born very preterm for developmental abnormalities,
in particular for cerebral palsy (CP) at 2 years in an everyday clinical setting.
METHOD: This is a multicentre study of infants born preterm with gestational age
lower than 32.0 weeks.
FMA was performed at 3 months corrected age;
neurodevelopment (Bayley Scales of Infant Development, 2nd edition) and
neurological abnormalities were assessed at 2 years.
Predictive values of FMA for
the development of CP were calculated and combined with abnormalities at cerebral
ultrasound. RESULTS: Five hundred and thirty-five infants (gestational age
28.2wks [standard deviation 1.3wks]) were included. Eighty-one percent showed
normal fidgety movements and 19% atypical (82 absent, 21 abnormal) fidgety
movements. Absent fidgety movements predicted CP at 2 years with an odds ratio
(OR) of 8.9 (95% confidence interval [CI] 4.1-17.0), a combination of atypical
fidgety movements and major brain lesion on cerebral ultrasound predicted it with
an OR of 17.8 (95% CI 5.2-61.6). Mean mental developmental index of infants with
absent fidgety movements was significantly lower (p=0.012) than with normal
fidgety movements. INTERPRETATION: Detection of infants at risk for later CP
through FMA was good, but less robust when performed in a routine clinical
setting; prediction improved when combined with neonatal cerebral ultrasound.
CI - (c) 2017 Mac Keith Press.

Langue : ANGLAIS