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MRI for in vivo diagnosis of cerebral amyloid angiopathy : Tailoring artifacts to image hemorrhagic biomarkers

BOULOUIS G; EDJLALI GOUJON M; MOULIN S; BEN HASSEN W; NAGGARA O; OPPENHEIM C; CORDONNIER C
REV NEUROL (Paris) , 2017, vol. 173, n° 9, p. 554-561
Doc n°: 184788
Localisation : Documentation IRR

D.O.I. : http://dx.doi.org/DOI:10.1016/j.neurol.2017.09.004
Descripteurs : AF2 - TROUBLES CIRCULATOIRES CEREBRAUX

Cerebral amyloid angiopathy (CAA) is a frequent age-related small vessel disease
(SVD) with cardinal magnetic resonance imaging (MRI) signatures that are
hemorrhagic in nature, and include the presence of strictly lobar (superficial)
cerebral microbleeds and intracerebral hemorrhages as well as cortical
superficial siderosis. When investigating a patient with suspected CAA in the
context of intracranial hemorrhage (parenchymal or subarachnoid) or cognitive
dysfunction, various MRI parameters influence the optimal detection and
characterization (and prognostication) of this frequent SVD. The present report
describes the influence of imaging techniques on the detection of the key
hemorrhagic CAA imaging signatures in clinical practice, in research studies, and
the imaging parameters that must be understood when encountering a CAA patient,
as well as reviewing CAA literature.
CI - Copyright (c) 2017 Elsevier Masson SAS. All rights reserved.

Langue : ANGLAIS

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