Article

OBJECTIVE: To examine the association between baseline mindfulness and response
from exercise interventions in knee osteoarthritis (OA). DESIGN: Cohort study;
responder analysis of a clinical trial subset. SETTING: Urban tertiary care
academic hospital. PARTICIPANTS: Participants with symptomatic, radiographic knee
OA (N=86; mean age, 60y; 74% female; 48% white). INTERVENTIONS: Twelve weeks
(twice per week) of Tai Chi or physical therapy exercise. MAIN OUTCOME MEASURES:
Treatment response was defined using Osteoarthritis Research Society
International criteria indicating meaningful improvements in the Western Ontario
and McMaster Universities Osteoarthritis Index (WOMAC) pain, WOMAC function, or
Patient Global Assessment scores. At baseline, participants completed the Five
Facet Mindfulness Questionnaire (mean total score, 142+/-17) and were grouped
into 3 categories of total mindfulness: higher, medium, or lower. Relative risk
(RR) ratios were used to compare treatment response across groups. RESULTS:
Participants with higher total mindfulness were 38% (95% confidence interval
[CI], 1.05-1.83) more likely to meet responder criteria than those with lower
mindfulness. We found no significant difference between medium and lower
mindfulness groups (RR=1.0; 95% CI, 0.69-1.44). Among the 5 mindfulness facets,
medium acting-with-awareness was 46% (95% CI, 1.09-1.96) more likely to respond
than lower acting-with-awareness, and higher acting-with-awareness was 34% more
likely to respond, but this did not reach significance (95% CI, 0.97-1.86).
CONCLUSIONS: In this study, higher mindfulness, primarily driven by its
acting-with-awareness facet, was significantly associated with a greater
likelihood of response to nonpharmacologic exercise interventions in knee OA.
This suggests that mindfulness-cultivating interventions may increase the
likelihood of response from exercise.
CI - Copyright (c) 2017 American Congress of Rehabilitation Medicine. Published by
Elsevier Inc. All rights reserved.

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