Article

Ultrasound (US) is a therapeutic modality that has been used in the treatment of
musculoskeletal conditions for decades. In recent years, there have been
technological advancements using low-intensity pulsed ultrasound (LIPUS) as a
clinical modality. The purpose of this review was to critically examine the
medical literature to determine the effects of LIPUS on the chondrogenic
properties of knee osteoarthritis. A literature search of 3 major databases
(PubMed, Scopus, and EMBASE) was performed. Two independent physician reviewers
screened titles and abstracts, yielding a total of 18 relevant articles after the
inclusion and exclusion criteria were applied. Results favored that LIPUS has a
promising effect on the cellular elements in articular cartilage, specifically on
chondrocytes in knee osteoarthritis. Although the use of LIPUS is encouraging
based on basic science and preclinical data, there is a paucity of evidence with
respect to humans. Consequently, there is insufficient evidence to recommend for
or against LIPUS in clinical OA populations. We suggest future directions for
research centered on LIPUS in both human and animal models to delineate the
effect on the biologic properties of cartilage in knee osteoarthritis. LEVEL OF
EVIDENCE: III.
CI - Copyright (c) 2017 American Academy of Physical Medicine and Rehabilitation.
Published by Elsevier Inc. All rights reserved.

Langue : ANGLAIS