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Clinical features of amyotrophic lateral sclerosis and their prognostic value

TARD C; DEFEBVRE L; MOREAU C; DEVOS D; DANEL BRUNAUD V
REV NEUROL (Paris) , 2017, vol. 173, n° 5, p. 263-272
Doc n°: 186633
Localisation : Documentation IRR

D.O.I. : http://dx.doi.org/DOI:10.1016/j.neurol.2017.03.029
Descripteurs : AE621 - SCLEROSE LATERALE AMYOTROPHIQUE

In classic amyotrophic lateral sclerosis (ALS), the relative degree of impairment
of cortical vs spinal motor neurons serving the different body regions is highly
variable. This means that an accurate, systematic assessment of the patient's
clinical presentation is essential for both the diagnosis and prognosis. The
patient's phenotype, rate of disease progression, time of onset (if early) of
respiratory failure and nutritional status all have prognostic value, and should
be specified in the nosological classification of the disease.
CI - Copyright (c) 2017 Elsevier Masson SAS. All rights reserved.

Langue : ANGLAIS

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