Article

The aim of the study was to evaluate the dosage effect of
low-intensity pulsed ultrasound stimulation on tendon-bone healing. DESIGN:
Standard partial patellectomies were performed on 120 mature New Zealand rabbits
randomly assigned into the following three groups: a control group (daily mock
sonication, 20 mins), a qd group (daily ultrasonication, 20 mins), and a bid
group (ultrasonication twice a day, 20 mins each time). The rabbits were killed 8
or 16 wks postoperatively, and the microarchitectural, histological, and
mechanical properties of the patella-patellar tendon interface were evaluated.
RESULTS: Microcomputed tomography analysis showed that the bid group exhibited
more new bone formation and mineralization than the other groups in the
tendon-bone healing position at both 8 and 16 wks postoperatively. Histological
assessments confirmed that the bid group exhibited a significantly better
patella-patellar tendon interface than the other groups, as shown by the
increased formation and remodeling of newly formed bone and a fibrocartilage
layer. The biomechanical properties of the regenerated patella-patellar tendon
interface significantly improved in the bid group. CONCLUSIONS: Low-intensity
pulsed ultrasound stimulation treatment twice a day was more effective than the
once-a-day treatment on tendon-bone healing.

Langue : ANGLAIS