Article

Unilateral neglect (UN) is a common debilitating consequence of
stroke. This review focused on the effect of noninvasive brain stimulation (NIBS)
techniques in the recovery of UN in poststroke patients. METHODS: Relevant
databases were comprehensively searched, including Cochrane Central Register of
Controlled Trials, Medline, Embase, the Web of Knowledge, and relevant websites.
All randomized controlled trials were identified which used NIBS for poststroke
UN. The methodological quality and risk of bias were systematically evaluated.
RESULTS: Twelve studies were included, and 11 randomized controlled trials were
made further meta-analysis. Participants who were randomized to active
transcranial direct current stimulation (effect size [ES], -0.51; 95% confidence
interval [CI], -1.02 to -0.01; P = 0.04) and repetitive transcranial magnetic
stimulation (ES, -1.76; 95% CI, -2.40 to -1.12; P < 0.00001) decreased UN
severity after intervention compared with the control group. Nonsignificant
pooled effect size presented for continuous theta burst stimulation results (ES,
-0.77; 95% CI, -1.90 to 0.37; P = 0.18). No participants experienced serious
adverse events. CONCLUSIONS: This review found evidence for the efficacy of
repetitive transcranial magnetic stimulation in the remediation of poststroke UN,
but the efficacy of transcranial direct current stimulation and continuous theta
burst stimulation was uncertain. Large-sample randomized controlled clinical
trials are needed to understand effects of NIBS on poststroke UN.

Langue : ANGLAIS