Article

Light physical activity is known to reduce atrial fibrillation risk,
whereas moderate to vigorous physical activity may result in an increased risk.
However, the question of what volume of physical activity can be considered
beneficial remains poorly understood. The scope of the present work was to
examine the relation between physical activity volume and atrial fibrillation
risk. Design A comprehensive systematic review was performed following the PRISMA
guidelines. Methods A non-linear meta-regression considering the amount of energy
spent in physical activity was carried out. The first derivative of the
non-linear relation between physical activity and atrial fibrillation risk was
evaluated to determine the volume of physical activity that carried the minimum
atrial fibrillation risk. Results The dose-response analysis of the relation
between physical activity and atrial fibrillation risk showed that physical
activity at volumes of 5-20 metabolic equivalents per week (MET-h/week) was
associated with significant reduction in atrial fibrillation risk (relative risk
for 19 MET-h/week = 0.92 (0.87, 0.98). By comparison, physical activity volumes
exceeding 20 MET-h/week were unrelated to atrial fibrillation risk (relative risk
for 21 MET-h/week = 0.95 (0.88, 1.02). Conclusion These data show a J-shaped
relation between physical activity volume and atrial fibrillation risk. Physical
activity at volumes of up to 20 MET-h/week is associated with reduced atrial
fibrillation risk, whereas volumes exceeding 20 MET-h/week show no relation with
risk.

Langue : ANGLAIS