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Comparing Corticosteroid Preparation and Dose in the Improvement of Shoulde Function and Pain

CARROLL MB; MOTLEY SA; SMITH B; RAMSEY BC; BAGGETT AS
AM J PHYS MED REHABIL , 2018, vol. 97, n° 6, p. 450-455
Doc n°: 187763
Localisation : Documentation IRR

D.O.I. : http://dx.doi.org/DOI:10.1097/PHM.0000000000000758
Descripteurs : DD36 - TRAITEMENTS - EPAULE, AD8 - DOULEUR

Shoulder pain may arise from inflammation of the bursa separating
the supraspinatus tendon from the coracoacromial ligament and acromion. The
optimal treatment dose and preparation of intrabursal corticosteroid injection
are unknown. METHODS:
This single-blinded equivalence study recruited 62 subjects
randomizing them to one of following four arms: methylprednisolone 20 mg,
methylprednisolone 40 mg, triamcinolone acetonide 20 mg, or triamcinolone
acetonide 40 mg. QuickDASH, subject-reported pain, and adverse events were
recorded in time of injection, 3 days later, 3 wks later, and 6 wks later.
Primary outcome was QuickDASH improvements 6 wks after injection. RESULTS: All
four groups were equally matched regarding age, sex, ethnicity, and site
injected. Six weeks after injection, no statistically significant changes were
noted in QuickDASH improvement (as compared with time of injection) among the
four arms. There were no statistically significant differences at 6 wks regarding
improvement in pain. There were no statistically significant differences noted in
adverse events among the four arms. CONCLUSIONS: Neither dose nor preparation of
injectable corticosteroid influences magnitude of improvement in function or pain
experienced. Although this study provides clinically relevant insight regarding
corticosteroid dose and type when managing shoulder pain, the modest sample size
may limit the conclusions that can be made about efficacy and adverse effects.

Langue : ANGLAIS

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