Article

Muscle degeneration in muscular dystrophies often includes a period of edema
before fatty replacement of muscle tissue. Magnetic resonance imaging (MRI) has
been used successfully to characterize muscle and fat patterns in several types
of muscular dystrophies.
Recent MRI techniques enable characterization of edema
in tissues. This article reviews the advantages of using MRI assessment of edema
and fat in muscle tissue to evaluate disease progression, and discusses
inflammation and sarcolemma compromise as sources of edema in muscular dystrophy.
Lastly, refining current techniques and adapting other MRI capabilities may
enhance detection and assessment of edema for better evaluation of disease
progression and treatment outcomes.
CI - Copyright (c) 2012 Elsevier Inc. All rights reserved.

Langue : ANGLAIS