Article

The brain is a plastic organ with a capability to reorganize in response to
behavior and/or injury. Following injury to the motor cortex or emergent
corticospinal pathways, recovery of function depends on the capacity of surviving
anatomical resources to recover and repair in response to task-specific training.
One such area implicated in poststroke reorganization to promote recovery of
upper extremity recovery is the premotor cortex (PMC).
This study reviews the
role of distinct subdivisions of PMC: dorsal (PMd) and ventral (PMv) premotor
cortices as critical anatomical and physiological nodes within the neural
networks for the control and learning of goal-oriented reach and grasp actions in
healthy individuals and individuals with stroke. Based on evidence emerging from
studies of intrinsic and extrinsic connectivity, transcranial magnetic
stimulation, functional neuroimaging, and experimental studies in animals and
humans, the authors propose 2 distinct patterns of reorganization that
differentially engage ipsilesional and contralesional PMC. Research directions
that may offer further insights into the role of PMC in motor control, learning,
and poststroke recovery are also proposed.
This research may facilitate
neuroplasticity for maximal recovery of function following brain injury.

Langue : ANGLAIS