Article

Osteoarthritis is the most common form of arthritis and is one of the leading
causes of disability in older adults. The measures of disease progression
currently being used to better understand the disease pathogenesis and to measure
structural change in clinical trials are most clearly documented in late stages
of disease and not early in the disease process, when intervention may be more
effective. A large number of epidemiologic and clinical trials currently are
underway to identify the most valid and responsive set of end points. Recent
studies have provided unique insights into the relationship between the structure
identified on imaging and symptom and disease genesis. The purpose of this
narrative review is to briefly consider radiographic developments, appraise the
developments in magnetic resonance imaging as it pertains to osteoarthritis, and
suggest potential areas for further development.
CI - Copyright (c) 2012 American Academy of Physical Medicine and Rehabilitation.
Published by Elsevier Inc. All rights reserved.

Langue : ANGLAIS