Article

Osteoarthritis (OA) is the most frequent cause of disability in the United
States, with the medial compartment of the knee being most commonly affected. The
initiation and progression of knee OA is influenced by many factors, including
kinematics. In response to loading during weight-bearing activity, cartilage in
healthy knees demonstrates spatial adaptations in morphology and mechanical
properties. These adaptations allow certain regions of the cartilage to respond
to loading; other regions are less well suited to accommodate loading.
Alterations in normal knee kinematics shift loading from cartilage regions
adapted for loading to regions less well suited for loading, which leads to the
initiation and progression of degenerative processes consistent with knee OA.
Kinematic variables that are associated with the development, progression, and
severity of knee OA are the adduction moment and tibiofemoral rotation. Because
of its strong correlation with disease progression and pain, the peak adduction
moment during gait has been identified as a target for treatment design. Gait
modification offers a noninvasive option for seeking significant reductions. Gait
modification has the potential to reduce pain and slow the progression of medial
compartment knee OA.
CI - Copyright (c) 2012 American Academy of Physical Medicine and Rehabilitation.
Published by Elsevier Inc. All rights reserved.

Langue : ANGLAIS