Article

Pratique basée sur les faits
- Regenerative therapy involves the injection of a small volume of solution into
multiple sites of painful ligament and tendon insertions (entheses) and adjacent
joint spaces, with the goal of reducing pain and ostensibly promoting tissue
repair and growth. Dextrose and platelet-rich plasma solutions have been shown to
increase expression of growth factors in vivo and have shown promising clinical
results in the treatment of tendinosus. In the treatment of osteoarthritis, small
clinical trials and case series to date suggest safety, symptomatic improvement,
and functional improvement at up to a year of follow-up; however, most of these
studies are uncontrolled. Given the methodological limitations of clinical
research on regenerative injections for osteoarthritis to date, this treatment
should be considered only after execution of a comprehensive assessment and
treatment plan, including optimization of biomechanics, weight loss,
cardiovascular exercise, resistance training, and judicious use of more
established topical, oral, and injectable medications.
CI - Copyright (c) 2012 American Academy of Physical Medicine and Rehabilitation.
Published by Elsevier Inc. All rights reserved.

Langue : ANGLAIS