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Frequency of domain-specific cognitive impairment in sub-acute and chronic stroke

MIDDLETON LE; LAM B; FAHMI H; BLACK SE; MCILROY WE; STUSS DT; DANELLS C; WEEN J; TURNER GR
NEUROREHABILITATION , 2014, vol. 34, n° 2, p. 305-312
Doc n°: 172196
Localisation : Centre de Réadaptation de Lay St Christophe

D.O.I. : http://dx.doi.org/DOI:10.3233/NRE-131030
Descripteurs : AD6 - MANIFESTATIONS NEUROCOMPORTEMENTALES - FONCTIONS COGNITIVES, AF21 - ACCIDENTS VASCULAIRES CEREBRAUX

Functional contributions of cognitive impairment may vary by domain
and severity. OBJECTIVE: (1) To characterize frequency of cognitive impairment by
domain after stroke by severity (mild: -1.5 </= z-score < -2; severe: Z </= -2)
and time (sub-acute: < 90d; chronic: 90d-2yrs); and (2) To assess the association
of cognitive impairment with function in chronic stroke. METHODS: Cognitive
function was characterized among 215 people with sub-acute or chronic stroke
(66.8 years, 43.3% female). Z-scores by cognitive domain were determined from
normative data. Function was defined as the number of IADLs minimally
independent. RESULTS: 76.3% of sub-acute and 67.3% of chronic stroke participants
had cognitive impairment in >/= 1 domain (p-for-difference = 0.09). Severe
impairment was most common in psychomotor speed (sub-acute: 53.5%; chronic:
33.7%). Impairment in executive function was common (sub-acute: 39.5%; chronic:
30.7%) but was usually mild. Severe impairment in psychomotor speed, visuospatial
function, and language and any impairment in executive function and memory was
associated with IADL impairment (p < 0.03). CONCLUSIONS: Mild cognitive
impairment is common after stroke but is not associated with functional
disability. Impairment in psychomotor speed, executive function, and visuospatial
function is common and associated with functional impairment so should be a focus
of screening and rehabilitation post-stroke.

Langue : ANGLAIS

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