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Improving activities of daily living ability in women with fibromyalgia - An exploratory, quasi-randomized, phase-two study, IMPROvE trial

VON BULOW C; AMRIS K; BANDAK E; DANNESKIOLD SAMSOE B; WAEHRENS EE
J REHABIL MED , 2017, vol. 49, n° 3, p. 241-250
Doc n°: 182926
Localisation : Documentation IRR

D.O.I. : http://dx.doi.org/DOI:10.2340/16501977-2198
Descripteurs : DA526 - FIBROMYALGIE, JG -ACTIVITES DE LA VIE QUOTIDIENNE - HANDICAP

OBJECTIVE: To explore and compare the outcomes of adaptation and physical
activity programmes regarding activities of daily living (ADL) ability following
interdisciplinary rehabilitation in women with fibromyalgia. METHODS:
Participants (n = 85) were quasi-randomized to 16-week adaptation (ADAPT) or
physical activity (ACTIVE) programmes following 2-week interdisciplinary
rehabilitation. Primary outcomes were ADL motor and ADL process ability, measured
with the Assessment of Motor and Process Skills (AMPS) at 4-week follow-up. Data
were analysed per protocol. RESULTS: Participants (ADAPT, n = 21; ACTIVE, n = 27)
did not differ from withdrawers (n = 37). Improvements in ADL ability in the
ADAPT (ADL motor mean change = 0.43 logits (95% confidence interval (95% CI) =
0.31-0.56); ADL process mean change = 0.34 logits (95% CI = 0.17-0.52)) and
ACTIVE (ADL motor mean change = 0.33 logits (95% CI = 0.22-0.43); ADL process
mean change = 0.25 logits (95% CI = 0.12-0.38)) groups were statistically
significant, with no differences between groups. Responder analyses revealed that
63% of all participants obtained clinically relevant improvements in ADL motor
ability and 48% in ADL process ability. CONCLUSION: Although limited by a large
drop-out, this exploratory study showed that both adaptation and physical
activity programmes following interdisciplinary rehabilitation improved ADL
ability in the majority of participants. ADL ability outcomes were independent of
group allocation (ADAPT vs ACTIVE), suggesting efficacy of both programmes.

Langue : ANGLAIS

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