Article

Traumatic brain injury (TBI) is one of the leading causes of morbidity and
mortality in the United States. One of the most common comorbidities of TBI is
the disruption of normal sleep. While often viewed as a nuisance symptom, sleep
disruption can delay TBI recovery and negatively affect many of the psychological
(e.g., anxiety, depression) and neuromuscular (e.g., pain) sequelae of TBI,
decreasing quality of life. Treatment of sleep disruption in the context of TBI
is complicated by issues of an altered neuronal milieu, polypharmacy, and the
complex relationship between the various comorbidities often found in patients
with TBI. Given the growing number of veterans returning from combat with TBI and
the elevated risk of comorbid disrupted sleep, both caused by and independent of
TBI, a comprehensive review of sleep disruption and its treatment is of great
relevance to the Department of Veterans Affairs.

Langue : ANGLAIS