Article

The progressive resistance exercise (PRE) in Parkinson's disease
trial (PRET-PD) showed that PRE improved the motor signs of PD compared to a
modified Fitness Counts (mFC) program. It is unclear how long-term exercise
affects physical function in these individuals. Objective. To examine the effects
of long-term PRE and mFC on physical function outcome measures in individuals
with PD. Methods. A preplanned secondary analysis was conducted using data from
the 38 patients with idiopathic PD who completed the PRET-PD trial. Participants
were randomized into PRE or mFC groups and exercised 2 days/week up to 24 months.
Blinded assessors obtained functional outcomes on and off medication at baseline,
6 and 24 months with the Modified Physical Performance Test, 5 times sit to stand
test, Functional Reach Test, Timed Up and Go, Berg Balance Scale, 6 minute walk
test (6MWT), and 50-ft walking speed (walk speed). Results.
The groups did not
differ on any physical function measure at 6 or 24 months (Ps > .1). Across time,
all physical function measures improved from baseline to 24 months when tested on
medication (Ps < .0001), except for 6MWT (P = .068). Off medication results were
similar except that the 6MWT was now significant. Conclusions. Twenty-four months
of supervised and structured exercise (either PRE or mFC)
is effective at
improving functional performance outcomes in individuals with moderate PD.
Clinicians should strive to include structured and supervised exercise in the
long-term plan of care for individuals with PD.
CI - (c) The Author(s) 2014.

Langue : ANGLAIS