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Impact of sleep-related breathing disorders on health-related quality of life in patients with chronic heart failure
SKOBEL E; NORRA C; SINHA A; BREUER C; HANRATH P; STELLBRINK C
EUR J HEART FAIL , 2005, vol. 7, n° 4, p. 505-511 Doc n°: 121160 Localisation : Documentation IRR Descripteurs : FA31 - INSUFFISANCE CARDIAQUE, JF - QUALITE DE VIE Quality of life in patients with chronic heart failure (HF) is often severely compromised. Sleep-related breathing disorders (SRBD) like Cheyne-Stokes Respiration (CSR) or obstructive sleep apnea (OSAS) are often observed in patients with severe HF resulting in fragmentation of sleep, excessive daytime sleepiness and an increased mortality. While an apnea/hypopnea-index (AHI) > 30/h represents an independent predictor of poor prognosis, clinical relevance of even minor SRBD with an AHI < 30/h remains unclear with respect to quality of life, exercise capacity or depression rate. Methods: Sixty-nine consecutive ambulatory patients with stable HF (NYHA II-III, EF 25%) underwent two night polygraphies with a six-channel ambulatory recording. Spiroergometry was performed, and patients were examined for sleep quality (PSQI), depressed mood (BDI) and health-related quality of life (SF-36). The data were compared to 10 age-matched healthy controls and 11 patients with OSAS (AHI 14-29/h) not suffering from HF. Results: Fifty-one patients completed follow up. 52% were positively diagnosed for SRBD (AHI 16-30/h: 12 patients CSR, 5 patients OSAS, 9 patients mixed); Langue : ANGLAIS Tiré à part : OUI |
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