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Neuroimaging patterns associated with motor control in traumatic brain injury
LOTZE M; GRODD W; RODDEN FA; GUT E; SCHONLE P; KARDATZKI B; COHEN LG
NEUROREHABIL NEURAL REPAIR , 2006, vol. 20, n° 1, p. 14-23 Doc n°: 123819 Localisation : Documentation IRR Descripteurs : AF3 - TRAUMATISME CRANIEN, AK15 - IRM Objective. To determine if patients with traumatic brain injury (TBI) and motor deficits show differences in functional activation maps during repetitive hand movements relative to healthy controls. Are there predictors for motor outcome in the functional maps of these patients? Methods. In an exploratory cross-sectional study, functional magnetic resonance imaging (fMRI) was used to study the blood-oxygenation-level-dependent (BOLD) response in cortical motor areas of 34 patients suffering from moderate motor deficits after TBI as they performed unilateral fist-clenching motions. Twelve of these patients with unilateral motor deficits were studied 3 months after TBI and a 2nd time approximately 4 months later. Results. Compared to age-matched, healthy controls performing the same task, TBI patients showed diminished fMRI-signal change in the primary sensorimotor cortex contralateral to the moving hand (cSM1), Langue : ANGLAIS |
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