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Clinical trial of a formal group fatigue program in multiple sclerosis

HUGOS CL; COPPERMAN LF; FULLER B; YADAV V; LOVERA J; BOURDETTE DN
MULT SCLER , 2010, vol. 16, n° 6, p. 724-732
Doc n°: 147393
Localisation : Documentation IRR

D.O.I. : http://dx.doi.org/DOI:10.1177/1352458510364536
Descripteurs : AE3 - SEP

Fatigue : Take Control is a novel program to teach fatigue management to people
with multiple sclerosis (MS) following recommendations in the Fatigue and
Multiple Sclerosis guideline. Fatigue: Take Control includes six 2-hour group
sessions with DVD viewing, discussion and homework and accompanying participant
and leader workbooks. While many people have participated in Fatigue: Take
Control programs, its efficacy has not been determined. The objective of this
study was to determine whether participation in Fatigue: Take Control reduces
fatigue and increases self-efficacy in people with MS. Thirty participants were
randomly assigned to a group who immediately participated in the program (FTC) or
a wait-list group (WL). The primary outcome was the Modified Fatigue Impact Scale
(MFIS) and secondary outcomes were the Multiple Sclerosis Self-Efficacy Scale
(MSSE) and the Fatigue Severity Scale (FSS). The MFIS was administered on 10
occasions. Other measures were administered on four occasions. A mixed model
tested the effects using all observations. Compared with the WL, the FTC group
had significantly more improvement on the MFIS [F(1, 269) = 7.079, p = 0.008] and
the MSSE [F(1, 111) = 5.636, p = 0.019]. No significant effect was found for the
FSS. Across all visits, fatigue was significantly lower and self-efficacy was
significantly higher for the FTC group compared with the WL group. This pilot
study demonstrated significant effects in fatigue and self-efficacy among
subjects taking the Fatigue: Take Control program, suggesting that this
comprehensive program based on the Fatigue and Multiple Sclerosis guideline may
be beneficial in MS.

Langue : ANGLAIS

Tiré à part : OUI

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