Article

The aim of the study was to investigate the risk of stroke in patients with
cerebral palsy (CP), based on nationwide data in Taiwan. METHOD: This prospective
cohort study was comprised of patients recorded on the Taiwan Longitudinal Health
Insurance Database 2005 (LHID2005) who had a diagnosis of CP (n=1975) in records
between 1 January 2004 and 31 December 2007. A comparison group (1:5) drawn from
the same database was matched for age and sex (n=9875).
Each patient was tracked
by data until the development of stroke or the end of 2008. Cox
proportional-hazards regression analysis was used to evaluate the hazard ratios
after adjusting for potential confounding factors. RESULTS: Patients with CP were
more likely to suffer stroke than the comparison population, after adjusting for
potential confounding factors (adjusted hazard ratio: 2.17; 95% confidence
interval [CI]: 1.74-2.69). The hazard ratio of stroke was 4.78 (95% CI:
3.18-7.17) and 1.57 (95% CI: 1.20-2.05) for patients with CP aged 50 years and
under, and over 50 years respectively. INTERPRETATION: Cerebral palsy is a risk
factor or marker for stroke that is independent of traditional stroke risk
factors. Further research in this area is warranted.
CI - (c) 2016 Mac Keith Press.

Langue : ANGLAIS