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Outcome following traumatic brain injury in the elderly
RAPOPORT MJ; FEINSTEIN A
BRAIN INJ , 2000, vol. 14, n° 8, p. 749-761 Doc n°: 97025 Localisation : Documentation IRR Descripteurs : AF3 - TRAUMATISME CRANIEN, MA - GERONTOLOGIE The elderly are at risk for traumatic brain injury (TBI), but their outcome following these injuries remains unclear. OBJECTIVE: This paper critically reviews research done to date on cognitive and functional outcome following TBI in the elderly. METHODS: MEDLINE and PSYCHLIT databases going back to 1965 were searched. RESULTS: Studies suggest that TBI results in adverse cognitive and functional outcomes in the elderly. There is uncertainty as to whether TBI is a significant risk factor for Alzheimer's disease (AD). Methodological problems in these studies include selection bias, small samples, retrospective analyses, and, particularly, the failure to address the role of pre-morbid functioning. These problems limit the strength of the outcome studies, and may account for the equivocal findings on AD risk. CONCLUSIONS: It is premature to conclude from the published research to date that the elderly have a uniformly poor outcome following TBI. Directions for further research are suggested. Langue : ANGLAIS Tiré à part : OUI Identifiant basis : 2000212950 |
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