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Utility of cardiopulmonary stress testing in assessing disease severity in children with pulmonary arterial hypertension
YETMAN AT; TAYLOR AL; DORAN A
AM J CARDIOL , 2005, vol. 95, n° 5, p. 697-699 Doc n°: 118117 Localisation : Documentation IRR Descripteurs : FB311 - HYPERTENSION ARTERIELLE, FC2 - HYPERTENSION PULMONAIRE This study sought to assess the safety of cardiopulmonary stress testing in 40 children with pulmonary arterial hypertension and to compare exercise responses in this patient cohort with those of a healthy control population. Patients with pulmonary hypertension had significant impairment in aerobic capacity, with a peak oxygen consumption of 20.7 +/- 6.9 versus 35.5 +/- 7.4 ml/kg/min in healthy controls (p < 0.0001). Peak oxygen consumption was strongly correlated with invasive measures of disease severity, including pulmonary vascular resistance index (r = -0.6, Langue : ANGLAIS Tiré à part : OUI |
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