Article

Impact of healthy lifestyle on cardiovascular risk
and mortality in people without a history of cardiovascular disease and without
elevation of lipid, blood pressure, or inflammatory markers. DESIGN: Cohort
study. METHODS: Study of a diverse sample of adults in the NHANES III follow-up
Mortality Survey, to determine the benefit of adhering to healthy lifestyle
habits (five or more fruits and vegetables/day, regular exercise, or being
non-obese (body mass index 18.5-29.9 kg/m(2)), no current smoking, moderate
alcohol consumption) in adults without common cardiovascular risk factors such as
elevated cholesterol (low-density lipoprotein, LDL, cholesterol >130 mg/dl),
inflammation (C-reactive protein, CRP, >3.0 mg/l, or hypertension (blood pressure
>140/90 mmHg). RESULTS: Of 11,841 participants, 14.9% were adherent to all five
healthy habits. After controlling for age, race, and gender, individuals with
lower LDL cholesterol (HR 6.33, 95% CI 2.80-14.30), low CRP (HR 3.48, 95% CI
2.23-5.41), or normal blood pressure (HR 2.87, 95% CI 1.58-5.20) and 0-1 healthy
habits had significantly higher all-cause (shown) and cardiovascular mortality
than people adhering to all five healthy habits. People without common risk
factors and lacking only 1-2 of the healthy habits remained at higher risk of
all-cause mortality. CONCLUSIONS: People without a history of cardiovascular
disease who lack common cardiovascular risk factors remain at significantly
greater risk of cardiovascular and all-cause mortality if they do not adhere to a
healthy lifestyle. Strategies to encourage adopting healthy lifestyles should be
implemented among individuals across all risk levels.

Langue : ANGLAIS

Tiré à part : OUI