Article

OBJECTIVE: To evaluate the effect of noninvasive ventilation (NIV) on exercise
performance in individuals with heart failure (HF).
DESIGN: Crossover, blind,
randomized controlled trial with allocation concealment. SETTING:
University-based research laboratory. PARTICIPANTS: Participants (N=24) with New
York Heart Association class II and III left heart failure and with a mean age of
51.8+/-10.2 years (women: n=8; men: n=16). INTERVENTIONS: Ventilatory support
attached to the face of the individual via a facemask prior to cardiopulmonary
exercise test (CPET) was administered at 2 pressure levels for 30 minutes.
Inspiratory pressure of 15cmH2O and expiratory pressure of 5cmH2O were applied.
MAIN OUTCOME MEASURES: Maximal oxygen uptake, maximum heart rate, variation
between the initial and maximum heart rates, CPET duration, and recovery time
oxygen consumption. RESULTS: Differences were observed in maximal oxygen
consumption (nonintervention phase: 18.3+/-4.4mL.kg(-1).min(-1) vs NIV phase:
20.6+/-4.9mL.kg(-1).min(-1), P=.01), heart rate (nonintervention phase:
127.3+/-20.9 beats per minute vs NIV phase: 134.7+/-19.5 beats per minute,
P=.04), and heart rate variation (nonintervention phase: 63.3%+/-19.3% vs NIV
phase: 69.7%+/-16.6%, P=.02). Moreover, differences in cardiopulmonary exercise
time (nonintervention phase: 7.4+/-1.5min vs NIV phase: 8.3+/-1.7min, P=.01) and
oxygen consumption recovery time (nonintervention phase: 2.8+/-1.0min vs NIV
phase: 2.4+/-0.8min, P=.01) were observed. CONCLUSIONS: NIV elicited beneficial
effects in the HF population that included increased exercise tolerance, recovery
time optimization, and improved chronotropic and respiratory reserves.
CI - Copyright (c) 2016 American Congress of Rehabilitation Medicine. Published by
Elsevier Inc. All rights reserved.

Langue : ANGLAIS