Article

Summarizing the evidence on the effects of pre- and postoperative
exercise and psychosocial rehabilitation interventions on patient-reported
outcomes (PROs) and physical fitness in bladder cancer patients undergoing
radical cystectomy. DATA SOURCES: The Cochrane Central Register of Controlled
Trials, MEDLINE, Embase, Web of Science and the Physiotherapy Evidence Database
were searched independently by two authors from inception until 10 November 2017.
Cited references of the studies and citing references retrieved via Web of
Science were also checked. REVIEW METHODS: Randomized controlled trials (RCTs)
and non-randomized studies assessing effects of exercise and psychosocial
interventions in bladder cancer patients undergoing radical cystectomy were
eligible. Primary outcome measures were PROs and physical fitness. Risk of bias
was assessed using the Cochrane Collaboration tool and the Newcastle-Ottawa
Scale. RESULTS: Five RCTs (three exercise and two psychosocial studies) and one
non-randomized psychosocial study comprising 317 bladder cancer patients were
included. Timing of the intervention was preoperative ( n = 2), postoperative ( n
= 2) or both pre- and postoperative ( n = 2). Positive effects of exercise were
found for physical fitness ( n = 3), some health-related quality-of-life (HRQoL)
domains ( n = 2), personal activities in daily living ( n = 1) and muscle
strength ( n = 1). Psychosocial interventions showed positive effects on anxiety
( n = 1), fatigue ( n = 1), depression ( n = 1), HRQoL ( n = 1) and posttraumatic
growth ( n = 1). Quality assessment showed most shortcomings with sample sizes
and strong heterogeneity was observed between studies. CONCLUSION: The evidence
relating to the effects of exercise in bladder cancer is very limited and is even
less for psychosocial interventions.

Langue : ANGLAIS