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Successful treatment of severe abulia with co-beneldopa

BAKHEIT AM; FLETCHER K; BRENNAN GP
NEUROREHABILITATION , 2011, vol. 29, n° 4, p. 347-351
Doc n°: 160206
Localisation : Centre de Réadaptation de Lay St Christophe

D.O.I. : http://dx.doi.org/DOI:10.3233/NRE-2011-0711
Descripteurs : AF1 - ETUDES GENERALES - ENCEPHALE

Abulia is a disorder of the executive and frontal lobe function. It is
characterised by severe psychomotor slowing that is not due to depressive illness
or catatonic schizophrenia. Abulia is thought to be due to disruption of the
meso-cortico-limbic dopaminergic system. Preliminary evidence suggests that
patients with abulia may respond to treatment with dopaminergic drugs. We extend
this evidence by reporting a significant and sustained functional improvement in
a severely abulic patient after treatment with co-beneldopa (Madopar)

Langue : ANGLAIS

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