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Risperidone treatment of motor restlessness following anoxic brain injury
SILVER BV; COLLINS L; ZIDEK KA
BRAIN INJ , 2003, vol. 17, n° 3, p. 237-244 Doc n°: 109042 Localisation : Documentation IRR Descripteurs : AF3 - TRAUMATISME CRANIEN This paper examined the use of an atypical neuroleptic medication, risperidone, in reducing the excessive motor activity of an adolescent with an anoxic brain injury following cardiac arrest from a lightning strike. Lower extremity restlessness caused the patient to develop skin breakdown and interfered with healing of existing burns. DESIGN: Single-blind, placebo-controlled single-subject experimental design. INTERVENTION: Escalating doses of risperidone up to 1 mg and in combination with methylphenidate (10 mg) and amantidine (100 mg). RESULTS: The patient demonstrated a reduction in restlessness in response to the use of risperidone, which permitted wound healing. The addition of methlphenidate to risperidone led to a slight increase in attention to task. CONCLUSIONS: The use of the atypical neuroleptic medication, risperidone, may be considered as part of the armamentarium available to physicians treating restlessness in severe brain injuries. Langue : ANGLAIS Tiré à part : OUI Identifiant basis : 2003227140 |
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