Article

OBJECTIVE: To investigate the effect of functional status, measured using the
Modified Rankin Scale (MRS), at 3 months after stroke on survival in patients
with stroke. DESIGN: Cohort study. SETTING: Referral medical center.
PARTICIPANTS: Patients with stroke (N=1032). INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURE: Survival after stroke. RESULTS: The Kaplan-Meier survival curves
stratified by the 3-month MRS score showed 2 clear groups of patients with
3-month MRS scores of 0 to 3 (able to walk without assistance) and 4 or 5 (unable
to walk without assistance). Accordingly, we grouped the patients into a high
function (HF) group (3-month MRS<==3) and a low function (LF) group (3-month
MRS>==4). Multiple Cox regression analysis showed that the LF group had
significantly poorer survival (adjusted hazard ratio=4.69; 95% confidence
interval [CI], 2.89-7.60; P<.001) than the HF group. Other significant risk
factors of higher mortality were older age, history of diabetes mellitus, and
heart disease. CONCLUSIONS: This study showed a significant influence of the
3-month MRS score on stroke survival. Moreover, independent ambulation may be a
major determinant of a favorable survival prognosis. This finding suggests a
potential role of rehabilitation in promoting stroke survival by maximizing
ambulation function.
CI - Copyright (c) 2012 American Congress of Rehabilitation Medicine. Published by
Elsevier Inc. All rights reserved.

Langue : ANGLAIS