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Hémorragie intracérébrale chez trois adultes hémophiles : une complication sévere de l'hémophilie

SAGNIER S; THOMAS B; HUGUENIN Y; CASTET S; POLI M; DEBRUXELLES S; RENOU P; ROUANET F; SIBON I
REV NEUROL (Paris) , 2015, vol. 171, n° 4, p. 367-372
Doc n°: 173383
Localisation : Documentation IRR

D.O.I. : http://dx.doi.org/DOI:10.1016/j.neurol.2014.10.017
Descripteurs : AF21 - ACCIDENTS VASCULAIRES CEREBRAUX, MD - HEMOPHILIE

Intracranial hemorrhage (ICH) complications are uncommon at
hemophilic patients. OBSERVATIONS: We report three cases of ICH occurring in
hemophilic patients. Contributing factors were identified in two patients:
hemophilia severity, presence of inhibitor, hepatitis C virus infection, and high
blood pressure. No contributing factor was identified in the last patient.
CONCLUSION: Rapid diagnosis of ICH is crucial in hemophilic patients. A search
for contributing factors, both those specific to hemophilia, and those favoring
ICH in the general population, is essential to optimize therapeutic care.
Specific substitutive treatment for the deficient factor is a difficult
management challenge.
CI - Copyright (c) 2014 Elsevier Masson SAS. All rights reserved.

Langue : FRANCAIS

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