Article

The aim of this study was to review the distribution of neuroimaging
findings from a contemporary population cohort of individuals with cerebral palsy
(CP) and to facilitate standardization of imaging classification.
METHOD: Publications from 1995 to 2012 reporting imaging findings in population cohorts
were selected through a literature search, and review of the titles, abstracts,
and content of studies. Relevant data were extracted, including unpublished data
from Victoria, Australia. The proportions for each imaging pattern were
tabulated, and heterogeneity was assessed for all individuals with CP, and for
subgroups based on gestational age, CP subtype, and Gross Motor Function
Classification System level. RESULTS: Studies from three geographic regions met
the inclusion criteria for individuals with CP, and two additional studies
reported on specific CP subtypes. Brain abnormalities were observed in 86% of
scans, but were observed least often in children with ataxia (24-57%). White
matter injury was the most common imaging pattern (19-45%), although the
proportions showed high heterogeneity. Additional patterns were grey matter
injury (21%), focal vascular insults (10%), malformations (11%), and
miscellaneous findings (4-22%). INTERPRETATION: This review suggests areas where
further dialogue will facilitate progress towards standardization of neuroimaging
classification. Standardization will enable future collaborations aimed at
exploring the relationships among magnetic resonance imaging patterns, risk
factors, and clinical outcomes, and, ultimately, lead to better understanding of
causal pathways and opportunities for prevention.
CI - (c) 2013 Mac Keith Press.

Langue : ANGLAIS