Article

OBJECTIVE: To determine effects of Whole Body Vibration Exercise (WBVE)
associated with quadriceps resistance exercises (QRE) versus QRE only on pain,
physical function, biomarkers in serum and urine, activities of daily living
(ADL), and quality of life in patients with knee osteoarthitis (OA). DESIGN:
Randomized-controlled trial . SETTING: Rehabilitation medicine outpatient
department of West China Hospital, Chengdu, Sichuan, People's Republic of China.
SUBJECTS: Forty-nine patients were assigned to WBVE+QRE and 50 to QRE . MAIN
OUTCOME MEASURES: Primary outcomes included pain assessed with visual analogue
scale (VAS), Timed up & go test (TUG), 6-min walk distance test (6MWD), Western
Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Secondary
outcomes comprised range of motion, muscular strength,
serum COMP and urinary
CTX-II, Lequesne Index (LI), and SF-36. All outcomes were analyzed with mixed
effects regression. RESULTS: Compared with QRE, WBVE+QRE showed significantly
greater improvement in VAS at 4weeks ( p=0.03), in VAS ( p<0.01), 6MWD ( p=0.01),
WOMAC pain ( p=0.01), and WOMAC physical function ( p=0.02) at 16 weeks, and in
all primary outcomes at 24 weeks (all p<0.01). CONCLUSION:
Over a six months
period, WBVE in combination with QRE was superior to QRE in most outcomes.

Langue : ANGLAIS