Article

OBJECTIVES: To describe the time course of recovery of sit-to-stand function in
patients with intensive-care-unit-acquired muscle weakness and the impact of
recovery. METHODS: A cohort study in post-acute intensive care unit and
rehabilitation units. Patients with chronic critical illness and
intensive-care-unit-acquired muscle weakness were included. Sit-to-stand function
was measured daily, using a standardized chair height, defined as 120% of the
individual's knee height. RESULTS: A total of 150 patients were recruited
according to the selection criteria. The primary outcome of independent
sit-to-stand function was achieved by a median of 56 days (interquartile range
Q1-Q3 = 32-90 days) after rehabilitation onset and a median of 113 days
(Q1-Q3=70-148 days) after onset of illness. The final multivariate model for
recovery of sit-to-stand function included 3 variables: age (adjusted hazard
ratio (HR) = 0.96 (95% CI 0.94-0.99), duration of ventilation (HR=0.99 (95% CI
0.98-1.00) and Functional Status Score for the Intensive Care Unit (FSS-ICU)
(adjusted HR=1.12 (95% CI 1.08-1.16)). CONCLUSION: Rapid recovery of sit-to-stand
function for most patients with intensive-care-unit-acquired muscle weakness were
seen. The variables older age and longer duration of ventilation decreased, and
higher FSS-ICU increased the chance of regaining independent sit-to-stand
function.

Langue : ANGLAIS