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Effects of exercise on cardiovascular risk factors following stroke or transient
ischemic attack

D'ISABELLA NT; SHKREDOVA DA; RICHARDSON JA; TANG A
CLIN REHABIL , 2017, vol. 31, n° 12, p. 1561-1572
Doc n°: 185070
Localisation : Documentation IRR

D.O.I. : http://dx.doi.org/DOI:10.1177/0269215517709051
Descripteurs : AF21 - ACCIDENTS VASCULAIRES CEREBRAUX

This review aimed to investigate the effects of exercise-based
interventions on cardiovascular risk factors in individuals with stroke or transient ischemic attack. DATA SOURCES: MEDLINE, EMBASE, PsycINFO, and CINAHL were searched from inceptions to 28 December 2016. REVIEW METHODS: Randomized
controlled trials were included that involved exercise with or without other
interventions, included participants of any age, with diagnosis of transient
ischemic attack or stroke, at any stage of severity or time period following the
event, and reported cardiovascular risk factor outcomes. Review Manager (version
5.3) was used to aggregate data from all studies and from those involving only
exercise interventions. RESULTS: This review included 18 randomized controlled
trials (930 participants) in the qualitative synthesis, 14 of which were included
in the quantitative analysis (720 participants; ranging from 84 to 438
participants within individual meta-analyses). All interventions were effective
in reducing resting systolic blood pressure (mean difference (MD): -5.32 mmHg,
95% confidence interval (CI): -9.46 to -1.18, P = 0.01), fasting glucose (MD:
-0.11 mmol/L, 95% CI: -0.17 to -0.06, P < 0.0001), and fasting insulin (MD:
-17.14 pmol/L, 95% CI: -32.90 to -1.38, P = 0.03), and increasing high-density
lipoprotein cholesterol (MD: 0.10 mmol/L, 95% CI: 0.03-0.18, P = 0.008). Effects
were maintained following meta-analysis of only exercise interventions.
CONCLUSION: Findings suggest that exercise-based interventions are effective in
reducing systolic blood pressure, fasting glucose, and fasting insulin, and
increasing high-density lipoprotein cholesterol after stroke or transient
ischemic attack, providing evidence for their implementation as a strategy for
secondary prevention.

Langue : ANGLAIS

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