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Fracture prevalence in Duchenne muscular dystrophy
MCDONALD D; KINALI M; GALLAGHER A
DEV MED CHILD NEUROL , 2002, vol. 44, n° 10, p. 695-698 Doc n°: 106963 Localisation : Documentation IRR Descripteurs : AB311 - MYOPATHIE DE DUCHENNE DE BOULOGNE The objective of this study was to determine the prevalence, circumstances, and outcome of fractures in males with Duchenne muscular dystrophy (DMD) attending neuromuscular clinics. Three hundred and seventy-eight males (median age 12 years, range I to 25 years) attending four neuromuscular centres were studied by case-note review supplemented by GP letter or by interview at the time of clinic attendance. Seventy-nine (20.9%) of these patients had experienced fractures. Forty-one percent of fractures were in patients aged 8 to 11 years and 48% in independently ambulant patients. Falling was the most common mechanism of fracture. Upper-limb fractures were most common in males using knee-ankle-foot orthoses (65 %) while lower-limb fractures predominated in independently mobile and wheelchair dependent males (54% and 68% respectively). Twenty percent of ambulant males and 27% of those using orthoses lost mobility permanently as a result of the fracture. In a substantial proportion of males, the occurrence of a fracture had a significant impact on subsequent mobility. Langue : ANGLAIS Identifiant basis : 2003225044 |
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